Coenzyme Q10 treatment in infertile men with poor motility

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Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial

To evaluate the effectiveness of coenzyme Q10 treatment in improving semen quality in men with idiopathic infertility.


Patients underwent double-blind therapy with coenzyme Q10, 200 mg/day, or placebo; the study design was 1 month of run-in, 6 months of therapy or placebo, and 3 months of follow-up.

The exogenous administration of coenzyme Q10 increases the level of the same and ubiquinol in semen and is effective in improving sperm kinetic features in patients affected by idiopathic asthenozoospermia.