Fertility Research

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Thyroxine replacement during super-ovulation for in vitro fertilization: a potential gap in management? Objective: Our objective is to report observed changes in thyroid-stimulating hormone (TSH) in two patients undergoing super-ovulation for IVF.Design: Case report.Setting: Private assisted reproduction practices.Patient(s): Two hypothyroid women taking thyroxine replacement therapy undergoing super...
Increased expression of p21-activated kinase in adenomyosis The present study was designed to evaluate whether the expression of p21-activated kinase 1 (Pak1), which recently has been shown to be increased in the eutopic endometrium of women with endometriosis, is also increased in adenomyotic nodules as well as in the eutopic endometrium in women with...
Blastocyst quality scoring based on morphologic grading correlates with cell number Blastocyst quality score (BQS), first reported by Rehman et al., is a numerical blastocyst-morphology grading system based on the criteria established by Gardner and Schoolcraft. We demonstrate a positive correlation between the calculated BQS score and cell number by staining thawed human embryos...
Should all embryos from day 1 rescue intracytoplasmic sperm injection be transferred during frozen–thawed cycles? A retrospective analysis of a 5-year rescue intracytoplasmic sperm injection (ICSI) experience performed in 17 cases of complete IVF fertilization failure showed that the ongoing pregnancy rate per embryo transfer (ET) is much higher in a subsequent frozen–thawed cycles (40%, 2/5) than following a...
Zona pellucida birefringence in in vivo and in vitro matured oocytes Objective: To evaluate zona pellucida birefringence (ZPB) in immature and mature oocytes collected after controlled ovarian stimulation and to assess the influence of ZPB on oocyte development.Design: Prospective study.Setting(s): Private assisted reproduction centre.Patient(s): Thirty patients...
Effects of metformin plus simvastatin on polycystic ovary syndrome: a prospective, randomized, double-blind, placebo-controlled study Objective: To evaluate the effect of a combination of simvastatin and metformin on biochemical parameters in women with polycystic ovary syndrome (PCOS).Design: A prospective, randomized, double-blind, placebo-controlled study.Setting: University hospital.Patient(s): Eighty-four women with PCOS...
A randomized controlled study comparing carbon dioxide versus normal saline as distension media in diagnostic office hysteroscopy: is the distension with carbon dioxide a problem? Objective: To compare two distension media, carbon dioxide (CO2) and saline, with regards to patient discomfort and the adequacy of the panoramic view in diagnostic hysteroscopy by the vaginoscopic approach.Design: Randomized prospective study.Setting: Tertiary referral centers for gynecologic care...
Handbook of Family Planning and Reproductive Healthcare Glasier and Gebbie's Handbook of Family Planning and Reproductive Healthcare is a comprehensive review of the history of family planning services in the United Kingdom. Included in the options available to women is detailed information regarding abortion and the legal aspects of family planning. In...
Hematometra following laparoscopic resection of retrocervical and rectovaginal endometriosis Objective: To report a case of hematometra following laparoscopic resection of rectovaginal endometriosis extending to the cervix.Design: Case report.Setting: University hospital.Patient(s): A 31-year-old woman with endometriosis and infertility.Intervention(s): Combined laparoscopic and vaginal...
Markers of growth and development in primate primordial follicles are preserved after slow cryopreservation Objective: To investigate the effect of slow cryopreservation on the morphology and function of primate primordial follicles within ovarian tissue slices.Design: Fresh monkey ovarian tissue was frozen by slow cryopreservation and thawed for analysis of morphologic and functional parameters.Setting...