Fertility Research

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Significantly superior response in the right ovary compared with the left ovary after stimulation with follicle-stimulating hormone in a pituitary down-regulation regimen Objective: To compare the differences between the right and left ovarian responses in patients undergoing standard in vitro fertilization (IVF) treatment.Design: Prospective, observational study.Setting: A university hospital in Taiwan.Patient(s): Seven hundred eighty-nine consecutive patients...
Evaluation of endometrial activin A secretion for prediction of pregnancy after intrauterine insemination Objective: To measure activin A concentrations in uterine washing fluid collected from women with couple infertility undergoing intrauterine insemination (IUI).Design: Retrospective case-control study.Setting: Tertiary university center for women's care.Patient(s): Fifty women, of whom 25 became...
Effect of high environmental temperature on semen parameters among fertile men Objective: To evaluate the effect of high environmental occupational temperature on semen parameters of fertile men.Design: Prospective.Setting: Steel-casting plant.Patient(s): Ninety fertile workers exposed to a high temperature compared with 40 fertile workers working under ordinary conditions as...
Estrogen receptor beta gene +1730 G/A polymorphism in women with polycystic ovary syndrome Objective: To investigate whether the +1730 G/A polymorphism in the estrogen receptor (ER)-β gene is associated with susceptibility to polycystic ovary syndrome (PCOS).Design: Case–control study.Setting: University Department of Obstetrics and Gynecology.Patient(s): Women with (n = 138) or without...
A 1-year longitudinal study of psychological morbidity after miscarriage Objective: To examine the 1-year longitudinal course of psychological outcomes after miscarriage.Design: Longitudinal observational study.Setting: University-affiliated teaching hospital.Patient(s): 280 miscarrying women and 150 nonpregnant women.Intervention(s): Psychological outcomes were...
Association of adolescent obesity and lifetime nulliparity—The Study of Women's Health Across the Nation (SWAN) Objective: To evaluate whether adolescent obesity is associated with difficulties in becoming pregnant later in life.Design: Cross-sectional analysis of baseline data from a longitudinal cohort.Setting: Multiethnic, community-based observational study of U.S. women.Patient(s): Three thousand one...
Gonadotropin-releasing hormone agonist or human chorionic gonadotropin for final oocyte maturation in an oocyte donor program Objective: To compare leuprolide acetate to hCG as the trigger for final oocyte maturation in oocyte donor cycles.Design: Retrospective review.Setting: Academic IVF donor program.Patient(s): Thirty-two healthy oocyte donors aged 21–33 years with adequate ovarian reserve.Intervention(s): Donors were...
A GnRH agonist and exogenous hormone stimulation protocol has a higher live-birth rate than a natural endogenous hormone protocol for frozen-thawed blastocyst-stage embryo transfer cycles: an analysis of 1391 cycles Objective: To compare embryo and birth data in cryopreserved-thawed blastocyst-stage ET cycles between natural endogenous hormone cycles and exogenous hormone stimulation cycles.Design: Retrospective cohort analysis.Setting: Large academic assisted reproductive technology center.Patient(s): One...
Female obesity impairs in vitro fertilization outcome without affecting embryo quality Objective: To compare embryo quality and reproductive outcome in our IVF program according to the women's body mass index (BMI).Design: Retrospective study.Setting: University-affiliated infertility clinic, between January 2001 and April 2007.Patient(s): Women undergoing a total of 6,500 IVF–...
Does endometrial integrin expression in endometriosis patients predict enhanced in vitro fertilization cycle outcomes after prolonged GnRH agonist therapy? Objective: To determine whether endometrial expression of the integrin αvβ3 vitronectin can predict which endometriosis patient subgroup will benefit from pre-IVF cycle prolonged GnRH agonist (GnRHa) therapy.Design: Prospective randomized institutional review board approved pilot trial.Setting:...