Fertility Research

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ASSESSMENT OF TESTICULAR SPERM EXTRACTION (TESE) AND INTRACYTOPLASMIC SPERM INJECTION (ICSI) IN COUPLES WITH POST CHEMOTHERAPY NON-OBSTRUCTIVE AZOOSPERMIA (NOA) Cancer treatments involving chemotherapy and radiotherapy exert detrimental effects on spermatogenesis, which may be temporary or prolonged. The reference standard is cryopreservation of ejaculated sperm prior to chemotherapy. Although the importance of sperm cryopreservation is emphasized at...
HOW MANY EGGS DO I NEED? A COUNSELING TOOL FOR OOCYTE CRYOPRESERVATION (OC) BASED ON REAL-WORLD DATA OC is widely used for fertility preservation. Many models predict the live birth (LB) rate of OC, but real-world data is lacking. We reviewed our LBs from OC to develop an OC counseling tool based on real outcomes.
FERTILITY PRESERVATION BY SPERM BANKING BEFORE GONADOTOXIC TREATMENT: 26 YEARS OF EXPERIENCE Sperm banking before gonadotoxic treatment is the basic and most effective method of preserving reproduction, which can be used during adolescence. The communication summarizes 26 years of experience in the operation of an oncological sperm bank, analyzes spermiograms of oncological patients,...
EGG FREEZING UNSCRAMBLED: AUTOLOGOUS OOCYTE (AO) THAW OUTCOMES FROM OVER 500 PATIENTS (PTS) AT A LARGE ACADEMIC FERTILITY CENTER (FC) AO cryopreservation (cryo) is widely used, but published thaw data is scarce. We reviewed our elective AO thaws.
FREEZE NOW, SAVE LATER: A SART DATA COST-EFFECTIVENESS ANALYSIS OF PLANNED OOCYTE CRYOPRESERVATION CONSIDERING IDEAL FAMILY SIZE Previous studies have used single-center data to model the cost-effectiveness of planned oocyte cryopreservation (OC) as a strategy for deferred reproduction to achieve a single live birth (LB). The objective of this study was
FERTILITY INTENTION, COUNSELING AND TREATMENT IN FEMALE CANCER SURVIVORS There are over 400,000 reproductive-aged female cancer survivors in the USA at increased risk of reproductive dysfunction due to cancer treatment. Not all patients undergo fertility preservation prior to cancer therapy due to various reasons. It remains unclear whether female cancer survivors are...
THE IMPACT OF SULPHASALAZINE-BASED TREATMENT ON SEMEN QUALITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE To systematically review the clinical evidence of sulphasalazine (SASP)-based treatment on semen quality in patients with inflammatory bowel disease (IBD).
COMPLETE PURGING OF EWING SARCOMA FROM HUMAN OVARIAN CORTEX TISSUE FRAGMENTS BY INHIBITING THE mTOR PATHWAY WITH EVEROLIMUS To assess the use of Everolimus for the ex vivo purging of Ewing sarcoma metastases from human ovarian cortex before autotransplantation by inhibiting the mTOR pathway, without compromising ovarian tissue integrity.
FERTILITY PRESERVATION COUNSELING AND FAMILY PLANNING PRIOR TO AND DURING THE COVID-19 PANDEMIC The delivery of women’s healthcare has changed drastically with the onset of the COVID-19 pandemic. This has undoubtedly created significant uncertainties for those interested in conception counseling. In particular, fertility preservation (FP) is time-sensitive and often emergent or urgent for...
NEONATAL OVARIAN RESERVE FOLLOWING CHEMOTHERAPY EXPOSURE, EX VIVO MURINE MODEL To determine the impact of exposure to maternal serum chemotherapy on formation of the ovarian reserve.