Fertility Research

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In the article In the article by Punjani et al., “Male infertility and genitourinary birth defects: there is more than meets the eye” (Fertil Steril 2020;114:209–18), there was an error in the authors’ affiliations. The correct name for affiliation a is as follows. The authors apologize for this eror.
The impact of uterine septum on reproductive outcome—half-empty or half-full? Few clinical dilemmas in reproductive medicine have persisted over decades with little progress toward resolution. The impact of a uterine septum on reproductive outcome is one of the most important and, regrettably, one of the thorniest dilemmas, for a variety of reasons so familiar to us. First,...
Preoperative prediction of ureteral endometriosis without dilatation: instructions for use There is a major difference between the clinical presentations of endometriosis causing intestinal stenosis and endometriosis causing ureteral stenosis. Whereas a severe bowel stricture originating from endometriosis infiltration, by definition, gives rise to subocclusive symptoms, obstructive...
INFLAMMATORY PROTEINS AS PREDICTORS OF DIMINISHED OVARIAN RESERVE Infertility is associated with chronic inflammation, but the role of inflammatory changes in the development of diminished ovarian reserve (DOR) is not well understood. The goal of this pilot study was to compare the ability of circulating immune cytokines and traditional serum and ultrasound...
RISK OF ANTEPARTUM ADMISSIONS IN ART COMPARED TO SPONTANOUSLY CONCEIVED PREGNANCIES Over the past decade there has been a significant increase in the use of assisted reproductive technology (ART) across the United States. In 2017 there were 284,385 ART cycles performed and these cycles resulted in 78, 052 infants1. Multiple studies have identified an increase risk of preterm birth...
NEO GAMETOGENESIS VIA OOCYTE REPLICATION For women with diminished ovarian reserve or advanced maternal age, various approaches have been attempted to increase oocyte yield for the ultimate goal of achieving a genotyped offspring. Producing haploid parthenogenetic embryos can generate haploid pseudo-blastomere (HpB) useful for...
INDIVIDUAL CULTURE LEADS TO DECREASED BLASTULATION BUT DOES NOT AFFECT PREGNANCY OUTCOMES IN THE SETTING OF A SINGLE, VITRIFIED-WARMED EUPLOID BLASTOCYST TRANSFER While there is ongoing debate regarding ideal conditions in the embryology laboratory, it has been suggested that group culture protocols lead to higher quality embryos than protocols utilizing individual culture. This may be due to higher levels of beneficial embryotrophic factors in the group...
CLINICALLY RECOGNIZED ERROR RATE AFTER TRANSFER OF A SINGLE EMBRYO SCREENED BY NEXT-GENERATION SEQUENCING IS 0.06% Preimplantation genetic testing for aneuploidy (PGT-A) is routinely used to improve pregnancy outcomes in in vitro fertilization (IVF). Although next-generation sequencing (NGS) is the most accurate technology for aneuploidy testing to date, it remains subject to error. No study has yet evaluated...
AFTER MORPHOLOGY PRIORITIZATION PGT-A SHOULD IMPROVE IMPLANTATION RATES BY 10% There is much debate over the degree of improvement preimplantation genetic testing for aneuploidy (PGT-A) provides with regards to implantation rates compared to not testing embryos. This debate is further confused by theoretical examples leading to the conclusion that PGT-A should yield...
MANAGEMENT AND OUTCOMES OF CESAREAN SCAR DEFECTS (CSD) IN PATIENTS WITH SECONDARY INFERTILITY Following a cesarean section, a discontinuity or diverticulum, in the endometrium and myometrium at the anterior lower uterine segment may develop1. This diverticulum is referred to as a “cesarean scar defect” (CSD). These defects can present with a number of symptoms, including abnormal uterine...