Fertility Research

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Simplified two-step technique for transvaginal natural orifice transluminal endoscopic surgery To describe our simplified two-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES) and to demonstrate the application of the technique.
Is there a correlation between paternal age and aneuploidy rate? An analysis of 3,118 embryos derived from young egg donors To investigate a possible correlation between chromosomal aberrations and paternal age, analyzing embryos derived from young oocyte donors, with available preimplantation genetic testing for aneuploidy results from day 5/6 trophectoderm biopsy obtained by next-generation sequencing for all 24...
Compassionate embryo transfer: physician practices and perspectives To assess reproductive endocrinology and infertility (REI) physicians’ basic knowledge of compassionate embryo transfer, current practices, and perceived barriers to offering compassionate transfer.
High satisfaction among women undergoing oocyte retrieval without anesthesia in a well-selected patient population Transvaginal ultrasound-guided oocyte retrieval for assisted reproduction was first described in 1985 (1). The pain associated with oocyte retrieval has been attributed to the aspiration needle puncturing the vaginal tissue as well as the ovarian capsule, along with manipulation of the needle...
Cryopreservation of ovarian tissue works, but challenges remain Since its early days in the late 1990s, cryopreservation of ovarian tissue (OTC) has developed from being an experimental procedure offered to a select few to being a standard method of fertility preservation that is particularly relevant for young girls and adolescents and women in need of urgent...
Laparoscopic resection of functional, noncommunicating uterine horn in close approximation to functional hemiuterus To review the presentation of unicornuate uterus with a functional noncommunicating rudimentary uterine horn and a laparoscopic method of management, highlighting laparoscopic surgical techniques.
Shortcomings of an unphysiological triggering of oocyte maturation using human chorionic gonadotropin Final maturation of follicles has, in connection with ovarian stimulation and infertility treatment, traditionally been achieved by the administration of a human chorionic gonadotropin (hCG) bolus trigger of 5,000 to 10,000 IU. This trigger serves two purposes: induce oocyte maturation; and serve...
Intracytoplasmic sperm injection (ICSI) for non–male factor indications: a committee opinion Intracytoplasmic sperm injection, while typically effective for overcoming low or absent fertilization in couples with a clear abnormality of semen parameters, is frequently used in combination with assisted reproductive technologies for other etiologies of infertility in the presence of semen...
An effective method for trophectoderm biopsy using mechanical blunt dissection: a step-by-step demonstration To present an effective approach to trophectoderm biopsy for blastocysts of different stages and characteristics by mechanical blunt dissection (MBD).
Compassionate embryo transfer: part of a bigger question Hairston et al. present results from a cross-sectional survey of members of the Society for Reproductive Endocrinology and Infertility (SREI) exploring attitudes and practice related to “compassionate transfer” of frozen embryos (1). The practice of compassionate transfer is “the intentional...