Fertility Research

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Evaluation of the efficacy, safety, and clinically recommended dose of dienogest in the treatment of primary dysmenorrhea: a randomized, double-blind, multicenter, placebo-controlled study To evaluate the efficacy, safety, and clinically recommended dose of dienogest (DNG; 0.5 mg/d, 1 mg/d, and 2 mg/d) in the treatment of primary dysmenorrhea.
Ultrasound evaluation of seminiferous tubules: a promising prognostic tool for men with nonobstructive azoospermia undergoing microsurgical testicular sperm extraction Azoospermia, or the absence of spermatozoa in the semen, is present in up to 10% of men presenting with infertility. The majority of these men will have nonobstructive azoospermia (NOA), or impaired production of sperm. When present, testicular sperm can be used with in vitro fertilization and...
Does empiric superovulation improve fecundity in healthy women undergoing therapeutic donor insemination without a male partner? To evaluate whether superovulation improves fecundity in women undergoing therapeutic donor insemination (TDI).
Evaluation of peripheral and uterine immune status of chronic endometritis in patients with recurrent reproductive failure To investigate whether chronic endometritis (CE) affects the immune status of peripheral blood and endometrium in patients with recurrent reproductive failure (RRF).
Comparing the individual effects of metformin and rosiglitazone and their combination in obese women with polycystic ovary syndrome: a randomized controlled trial To compare the effects of metformin, rosiglitazone, and their combination in obese polycystic ovary syndrome (PCOS) patients with insulin resistance.
Clinical adjuncts in in vitro fertilization: a growing list A growing list of clinical adjuncts are being used during in vitro fertilization (IVF) treatment. Most of these IVF add-ons (such as growth hormone, aspirin, heparin, dehydroepiandrostenedione, testosterone, male and female antioxidants, and screening hysteroscopy) are being introduced into routine...
Do à la carte menus serve infertility patients? The ethics and regulation of in vitro fertility add-ons Add-on treatments are the new black. They are provided (most frequently, sold) to patients undergoing in vitro fertilization on the premise that they will improve the chances of having a baby. However, the regulation of add-ons is consistently minimal, meaning that they are introduced into routine...
Fecundability in relation to use of fertility awareness indicators in a North American preconception cohort study To quantify the frequency of use of selected fertility awareness indicators and to assess their influence on fecundability.
Lifting the endometrioma veil on granulosa cells The paper by Li et al. (1) in this issue examines the impact of ovarian endometriosis on granulosa cells, linking molecular physiology to fertility outcomes. An eloquent oocyte–granulosa cell dialog occurring within ovarian follicles supports the development of a mature oocyte to secure a competent...
Trying to conceive? Track your cycle—any method will do The scientific study of fertility tracking can be traced back to the early 1900s when Dutch gynecologist Theodoor Henrik van de Velde observed that basal body temperature rises in the days before menstruation (1). By the 1930s, these observations had been translated into calendar-based menstrual...