Fertility Research

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Podocalyxin inhibits human embryo implantation in vitro and luminal podocalyxin in putative receptive endometrium is associated with implantation failure in fertility treatment To study whether endometrial epithelial podocalyxin (PCX) inhibits implantation of human embryos in vitro and in patients undergoing in vitro fertilization (IVF).
COVID19 infection in pregnancy: a Spanish perspective of spontaneous and in vitro fertilization pregnancies As we continue to learn more about the adverse effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on perinatal outcomes, it is important to understand whether specific groups of pregnant women, including those who conceive using assisted reproductive technology (ART...
Development and validation of a risk prediction index for severe maternal morbidity based on preconception comorbidities among infertile patients To develop and validate a preconception risk prediction index for severe maternal morbidity (SMM), defined by the Centers for Disease Control and Prevention as indicators of a life-threatening complication, among infertile patients.
Ovarian stimulation protocols: don’t immediately change a losing team “Never change a winning team” is an often-used saying in football, attributed to Sir Alfred Ernest “Alf” Ramsey, who guided England to their only FIFA World Cup victory in 1966. In assisted reproductive technology (ART), based on the results of the study by Wald et al. (1), this may be modified to...
“Nerve-sparing” laparoscopic treatment of parametrial ectopic pregnancy To demonstrate laparoscopic surgical management of parametrial ectopic pregnancy.
Innovations in infertility: a comprehensive analysis of the ClinicalTrials.gov database To characterize the interventional clinical trials in infertility and to assess whether trial location or industry sponsorship was associated with trial noncompletion.
A machine learning algorithm can optimize the day of trigger to improve in vitro fertilization outcomes To determine whether a machine learning causal inference model can optimize trigger injection timing to maximize the yield of fertilized oocytes (2PNs) and total usable blastocysts for a given cohort of stimulated follicles.
Extracellular matrix remodeling and inflammatory pathway in human endometrium: insights from uterine leiomyomas To compare the expression profiles of matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitors of matrix metalloproteinases, TIMPs) in the endometrium of women with and without type 3 leiomyomas and to understand their relationship with inflammatory status.
Deoxyribonucleic acid methylation signatures in sperm deoxyribonucleic acid fragmentation To evaluate Deoxyribonucleic acid (DNA) methylation patterns in sperm from men with differential levels of sperm DNA fragmentation index (DFI).
Deoxyribonucleic acid methylation: measuring assisted reproductive technology outcomes beyond live birth rates The journey through infertility carries a high emotional toll, but treatment with assisted reproductive technology (ART) has provided successful options for family building. This success is often measured by live birth by both the patient and provider. Success, however, has its trade-offs. With an...