Fertility Research

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Frozen eggs: national autologous oocyte thaw outcomes To characterize national outcomes of oocyte thaw (OT) cycles.
Oscillations of estradiol and gonadotropins are a missing link to solving the mystery of mono-ovulation in humans Regulation of follicular development leading to mono-ovulation remains one of the unsolved mysteries of human reproduction. The current working hypothesis in part postulates that as multiple follicles grow, they produce estradiol, which exerts continued negative feedback on the follicle-stimulating...
Hysteroscopic treatment and reproductive outcomes in cesarean scar pregnancy: experience at a single institution To study the risk factors leading to type II/III cesarean scar pregnancy and evaluate the efficacy of hysteroscopic treatment and subsequent reproductive outcomes.
Potential later-life health implications of polycystic ovary syndrome are underserved and understudied Like many other syndromes, polycystic ovary syndrome (PCOS) represents a notoriously heterogeneous common condition, diagnosed in up to 20% of all women of reproductive age. In the early days, the more exclusive National Institutes of Health definition of PCOS that was used for diagnosis...
Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: part II, donor oocyte cycles To determine whether the ooplasm granulation patterns of donor oocytes, like those of oocytes from poor-prognosis patients, are predictive of in vitro fertilization (IVF) outcomes.
Reproductive medicine at the crossroads of stem cell biology and big-data Two of the most exciting and impactful areas of science today involve explorations into the ability of stem cells to regenerate failing organs or even create “new” organs, and the generation of expansive organ- and cell lineage-specific datasets that contain global snapshots of gene expression...
Conservative cesarean scar pregnancy treatment: local methotrexate injection followed by hysteroscopic removal with hysteroscopic tissue removal system To describe a conservative cesarean scar pregnancy (CSP) treatment in a patient with the desire for future pregnancy. To date, there is no gold standard for the management of a viable CSP. There is a wide range of treatment options that include major surgery and minimally invasive procedures....
Male vitamin D status and male factor infertility To determine the association between vitamin D levels in the male partner and fertility outcomes in couples with mild male factor infertility.
Surgical treatment of uterine septum to improve reproductive outcomes — resect or not? Septate uterus is the most common congenital uterine anomaly, accounting for 35% of such anomalies (1). The literature describing an association between septate uterus and infertility or pregnancy loss consists almost exclusively of retrospective studies, and the only randomized, controlled trial (...
Quantitative selection of single human sperm with high DNA integrity for intracytoplasmic sperm injection To study at the single-cell level whether a sperm’s motility and morphology parameters reflect its DNA integrity, and to establish a set of quantitative criteria for selecting single sperm with high DNA integrity.