Fertility Research

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Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review Providers who care for women at risk for hereditary gynecologic cancers must consider the impact of these conditions on reproductive and hormonal health. This document reviews potential options for cancer prevention, family building, genetic testing and management of surgical menopause in this...
Ovarian stimulation and assisted reproductive technology outcomes in women transplanted with cryopreserved ovarian tissue: a systematic review To systematically review reproductive outcomes of assisted reproductive technology (ART) treatment in women transplanted with frozen-thawed ovarian tissue.
Toward a standard definition of polycystic ovarian morphology Polycystic ovary syndrome (PCOS) is the most common cause of infertility due to anovulation. In general, women with PCOS exhibit features of menstrual irregularity, hyperandrogenism, and insulin resistance; however, the phenotypic spectrum is broad. Diagnostic inconsistencies and heterogeneous...
Another piece in the polycystic ovary syndrome-depression/anxiety puzzle: body image As our understanding of the complexity of polycystic ovary syndrome (PCOS) grows, we begin to appreciate the far-reaching, multi-system manifestations of this disorder. PCOS is beyond a solely gynecologic disturbance. In recent years, new light has illuminated several psychological comorbidities of...
Relugolix, a novel oral gonadotropin-releasing hormone antagonist, in the treatment of pain symptoms associated with uterine fibroids: a randomized, placebo-controlled, phase 3 study in Japanese women To investigate the efficacy and safety of the oral gonadotropin-releasing hormone receptor antagonist, relugolix, in patients experiencing uterine fibroid–associated pain.
Assisted reproductive technology outcomes in female-to-male transgender patients compared with cisgender patients: a new frontier in reproductive medicine To investigate assisted reproductive technology (ART) outcomes in a female-to-male transgender cohort and compare the results with those of a matched cisgender cohort.
Cumulus cells have longer telomeres than leukocytes in reproductive-age women To investigate whether telomere length (TL) in granulosa cells (GC) or cumulus cells (CC) correlates with TL in leukocytes (L).
Sperm microRNA pairs: new perspectives in the search for male fertility biomarkers To identify candidates of fertility biomarkers among pairs of human sperm microRNAs.
To eat soy or to not eat soy: the ongoing look at phytoestrogens and fertility Phytoestrogens, plant-derived compounds found predominantly in soy, and their overall reproductive health impact and safety remain hotly debated. Whether they have stimulatory or inhibitory effects on estrogen receptors is much more complicated than originally thought. There are numerous studies...
Artificial intelligence and the diagnosis of abnormal pregnancy: single nucleotide polymorphism away In a recent retrospective analysis by Maisenbacher et al. (1), the examination of products of conception (POCs) by single nucleotide polymorphism (SNP) array was used to determine the frequency of molar pregnancy in miscarriage. For the cohort of miscarriages where complete history and clinical...