Fertility Research

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Cost-effectiveness of preimplantation genetic testing for aneuploidies To evaluate the economical benefit of preimplantation genetic testing of aneuploidies (PGT-A) when applied in an extended culture and stringent elective single ET framework.
Diversity of international surrogacy arrangements: considerations for cross-border reproductive care As noted by Javda et al. in this issue of Fertility and Sterility, surrogacy is practiced in diverse ways (1). In gestational surrogacy, the woman who carries the pregnancy is solely a gestational carrier and has no genetic connection with the child. In contrast, with traditional surrogacy, a woman...
30 years of data: impact of the United States in vitro fertilization data registry on advancing fertility care To summarize and assess the impact of key research generated through the Society of Assisted Reproductive Technology (SART)-initiated United States IVF registry and annual reporting system.
In vitro fertilization and infertility do not cause a significant alteration in placental gene expression at the end of the first trimester Pregnancies achieved after fertility treatments are associated with an increased risk of adverse outcomes such as compromised placentation, perinatal complications, and birth defects (1, 2). Moreover, studies using animal models indicate that assisted reproductive technology (ART) procedures could...
Menstrual cyclicity is predictably unpredictable “Time moves slowly but passes quickly”— Alice Walker
Interplay of public perception and fertility guidelines Lee et al. (1) queried the public's perspectives on placing age limits on men and women seeking fertility treatment. Understanding the public's attitudes regarding management of infertility patients is relevant and necessary. Deviating significantly from what the public feels is acceptable puts...
Oocyte quantity and quality are crucial for a perspective of fertility preservation in women with Turner syndrome Affecting approximately 1 in 2,500 girls at birth, Turner syndrome (TS) is one of the most common chromosomal disorders, in which subjects are monosomic for the X chromosome (45,X) or, in a minority of cases, present with mosaicism for the simultaneous presence of a normal 46,XX cell line. TS is...
What if deep endometriotic nodules and uterine adenomyosis were actually two forms of the same disease? Some symptoms of endometriosis, such as severe dysmenorrhea, overlap with those of uterine adenomyosis, a disease characterized by growth of endometrium into the myometrium. From a histologic point of view, deep rectovaginal endometriotic nodules were described by Donnez et al. (1) back in 1996 as...
Letrozole versus clomiphene in polycystic ovary syndrome—more than one way to crack an egg Polycystic ovary syndrome (PCOS) is a common cause of anovulatory infertility. Optimal ovulation induction would achieve ovulation and live birth while minimizing the risk of multiple gestations, birth defects, side-effects, and cost. The optimal first-line agent has evolved based on several...
Introduction Surgical treatments offer effective solutions for many couples experiencing male factor infertility. This Views and Reviews collection of articles offers a state-of-the-art overview of the surgical procedures commonly used to treat impaired male reproductive health.