Fertility Research

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Big data meets the menstrual cycle Nearly a century ago, Ogino and Knaus separately and concurrently identified the timing of ovulation within the human menstrual cycle (1). Since then, many clinical and epidemiologic studies have elucidated details about the length of the cycle, the length of the follicular and luteal phases,...
Current controversies in tubal disease, endometriosis, and pelvic adhesion Reproductive surgery for proximal and distal tubal occlusion, as well as for reversal of tubal ligation, may be an alternative or an adjunct to IVF. Surgery for adenomyosis and endometriosis, including endometriomas, may be considered for the treatment of infertility and/or pelvic pain but carries...
Fertility-enhancing male reproductive surgery: glimpses into the past and thoughts for the future Over the past few decades, there have been numerous paradigm shifts in male reproductive surgery, resulting from a combination of technologic advancements in both the operating room and the laboratory. The operating microscope transformed the field of male reproductive surgery, enabling novel...
Postoperative adhesions in gynecologic surgery: a committee opinion Postoperative adhesions are a natural consequence of surgical tissue trauma and healing and may result in infertility, pain, and bowel obstruction. Adherence to microsurgical principles and minimally invasive surgery may help to decrease postoperative adhesions. Some surgical barriers have been...
Advances in fertility-preservation surgery: navigating new frontiers For female patients facing fertility-impairing treatment for select cancers and other medical conditions, fertility-preserving surgeries have evolved to meet the needs of those who desire fertility preservation. Over the last 70 years, advances in surgical options for fertility preservation have...
Reproductive surgery: glimpses into the past and thoughts for the future (part 2) This month's Views and Reviews continues with part two of the series regarding reproductive surgery. The roles of reproductive surgery in müllerian anomalies, tubal and pelvic disease, fertility preservation, and male reproductive surgery are included. Augmenting each contribution, authors have...
Reproductive surgery for müllerian anomalies: a review of progress in the last decade Disorders of development, fusion, or resorption of paired müllerian ducts and urogenital sinus may cause various congenital malformations of the corpus uteri, cervix, vagina, and fallopian tubes. Classification systems have been developed to better characterize these anomalies, and each has...
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Single-nucleotide polymorphism microarray detects molar pregnancies in 3% of miscarriages To determine the frequency of molar pregnancy in miscarriage cases based on single-nucleotide polymorphism (SNP) microarray testing on products of conception (POC) tissue and to estimate the sensitivity of ultrasound and histopathologic evaluation for cases identified to be at risk for gestational...