Fertility Research

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Expression of erythropoietin messenger ribonucleic acid in wild-type MED12 uterine leiomyomas under estrogenic influence: new insights into related growth disparities To determine factors that impact erythropoietin (EPO) production in leiomyomas. We have previously implicated EPO production in promoting the growth of some leiomyomas.
Higher luteinizing hormone levels associated with antimüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome To study the reproductive and metabolic differences between daughters of women with polycystic ovary syndrome (PCOSd) and control women (Cd) after menarche.
Vilaprisan in women with uterine fibroids: the randomized phase 2b ASTEROID 1 study To assess the safety and efficacy of four vilaprisan doses (0.5–4.0 mg) in women with uterine fibroids.
Pathogenesis of endometriosis: the genetic/epigenetic theory To study the pathophysiology of endometriosis.
Serum antimüllerian hormone is associated with the number of oocytes matured in vitro and with primordial follicle density in candidates for fertility preservation To assess whether serum antimüllerian hormone (AMH) levels and antral follicle count (AFC) can predict primordial follicle density within ovarian cortex and the number of oocytes cryopreserved after in vitro maturation (IVM).
Minimal difference in phenotype between adolescents and young adults with polycystic ovary syndrome To test the hypothesis that the polycystic ovary syndrome (PCOS) phenotype, or its component features, is less severe in adolescents than in young adult patients, in a referred (clinical) population.
Growth disparities in uterine leiomyomas associated with MED12 mutation Uterine leiomyoma is the most common benign estrogen (E)-dependent tumor in women of reproductive age. Approximately 25% of women are affected and the cumulative incidence is 70% of women by the age of 50 years. In addition, this tumor is more prevalent at younger ages, and is more common in...
BRCA carriers have similar reproductive potential at baseline to noncarriers: comparisons in cancer and cancer-free cohorts undergoing fertility preservation To investigate whether BRCA carriers with and without malignancy have decreased ovarian reserve at baseline compared with BRCA noncarriers.
Deoxyribonucleic acid detection in blastocoelic fluid: a new predictor of embryo ploidy and viable pregnancy To investigate blastocysts, defined as euploid and aneuploid by trophectoderm (TE) cell analysis, for the presence of DNA in the blastocoelic fluid (BF) detected by whole-genomic amplification (WGA); and to correlate the presence of DNA in BF with the clinical outcome after the transfer of TE-...
Acute effects of air pollutants on spontaneous pregnancy loss: a case-crossover study To investigate the relationship between acute exposure to air pollutants and spontaneous pregnancy loss.